Gastric cancer is the fourth most common cancer worldwide. Outside the United States, it is the third most common cause of cancer death. Early diagnosis of gastric cancer is critical in preventing cancer deaths. Currently there are no minimally invasive tests capable of early detection of gastric cancer or intestinal metaplasia. Therefore, we sought to identify a bioprofile that detects gastric cancer at the earliest stage possible.
Paradise Genomics rapidly discovers novel bioprofiles in blood or tissue using a disruptive process and proprietary platform of unparalleled utility in the diagnosis, prognosis, or therapeutic monitoring of any disease. We investigated the differential bioprofiles of gastritis, pre-cancerous metaplasia, and gastric cancer using whole blood.
Two distinct gene expression bioprofiles from a minimally invasive blood sample have high accuracy in identifying and distinguishing patients diagnosed with gastritis, metaplasia, or gastric cancer. These data demonstrate for the first time that bioprofiles in blood have the sensitivity and specificity necessary to directly diagnose cancer and pre-cancerous lesions. These bioprofiles are ready to be developed into clinical tests for screening, diagnosis, or monitoring therapy.
All patients presented with gastritis.
Their blood bioprofile correlated with pathological finding of gastritis, precancer or cancer.
Paradise Genomics seeks development and commercialization partners to quickly and successfully capitalize on current or future bioprofile discoveries. To discuss these or other bioprofile discoveries, please e-mail email@example.com for all inquiries.